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Our Scientific Foundation

 

At Biomine Health, everything we do is grounded in science. Our tests are built on over a decade of microbiome research, clinical insight, and computational biology.

We don’t just interpret microbiome data — we use rigorous scientific methods to generate it, analyse it, and translate it into personalised, actionable insights. Each insight in your report is backed by peer-reviewed studies, validated methodologies, and real-world data from diverse populations.

This page is designed to help you dive deeper into the science — whether you're simply curious or a health professional looking for transparency.

Here, you’ll find:

  • The science behind the Biomine platform — how we turn your sample into meaningful data

  • Key scientific papers shaping our understanding of the microbiome and its impact on health

  • Supporting studies that directly inform your personalised Biomine report

The Science Behind the Biomine Test

From swab to insights: our scientific process

Sample collction

You collect your sample at home using our validated swab kit, designed to protect microbial DNA during transport.

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Sequencing

In the lab, we extract and sequence microbial DNA using 16Sr RNA next generation sequencing 

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Analalysis & AI

Bioinformatics analysis and ML algorithms to model your data and extract meaningful patterns linked to health and function

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Report generation

Your results are translated into a personalised report with clear insights and guidance tailored to your microbiome.

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Featured Papers

Definition and Scope of Prebiotics

This paper redefines what prebiotics are, expanding beyond just fibers to include a broader range of compounds. It clarifies that prebiotics are substances selectively used by beneficial microbes to improve health.

The Interplay Between Diet and the Gut Microbiome

This comprehensive review explains how different diets—from Mediterranean to Western—shape the gut microbiome, and how these dietary-microbe interactions affect metabolic health, immunity, and disease risk.

Host and Microbiota Metabolic Signals in Ageing and Longevity

This review details how the metabolic dialogue between host and microbes changes over time. It explores how gut microbes can influence lifespan by modulating inflammation, mitochondrial function, and nutrient-sensing pathways.

Shaping the Future of Probiotics and Prebiotics

A broad, visionary review of where the fields of probiotics and prebiotics are heading. It explores new microbial candidates, mechanisms of action, regulatory trends, and how precision nutrition is shaping next-gen products like synbiotics and postbiotics.

Roles of the Gut Microbiome in Weight Management

The gut microbiome plays a critical role in how our bodies gain or lose weight. This paper explores how microbes influence energy balance, appetite, and fat storage—and how they may be harnessed for better long-term weight control.

The Gut Microbiota–Brain Axis in Behaviour and Disorders

This review unpacks how gut bacteria influence brain development and function. It connects microbial activity to mood, cognition, and disorders like autism and depression, highlighting the gut–brain axis as a promising target for future therapies.

Diet–Microbiota Interactions and Personalized Nutrition

This review explores how diet affects each person's microbiome in unique ways. It explains that a "one-size-fits-all" approach to nutrition doesn’t work, but rather, personalised diets based on your microbiome could improve health.

Impact on the Pathogenesis of Obesity and Beyond

This article examines how alterations in the gut microbiome contribute to obesity and its complications, including diabetes and metabolic syndrome. It discusses microbial mechanisms that affect fat storage, insulin sensitivity, and inflammation.

The Gut Microbiome as a Modulator of Healthy Ageing

Ageing alters the microbiome, but the microbiome also influences how we age. This paper explores how specific microbes and their metabolites can support healthier ageing and help prevent age-related diseases like frailty and cognitive decline.

Scientific References Behind Your Report

Microbiome Health
Microbial diversity
Dysbiosis index
Enterotype

Gut-Body Interaction
Gut-immune-axis
Inflammatory potential
Gut-skin-axis
Weight management

Digestive Health Conditions
Leaky gut
Irritable bowel syndrome
SIBO
Gluten sensitivity
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